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vomiting, injured jaw or throat, or gastrointestinal difficulties, it is still be possible to administer Cannabis rectally. Cannabis Suppositories: Is the Posterior Superior - www January 22, 2015 Suppositories are often the butt of many jokes and puns, but rectal administration of cannabis has many advantages. In addition to being a viable option for patients who can’t ingest or inhale cannabis, cannabis suppositories also begin to work quickly and last for a long time.